Arterial Disease, Angina, Blood Clots, Deep Vein Thrombosis DVT
What is it?
Arteriosclerosis (calcium deposits) and Atherosclerosis (fat deposits) involve a build-up on the inside of artery walls.
What causes it?
While there is overwhelming evidence that high levels of cholesterol increases the risk of developing Atherosclerosis, Angina, DVT and Blood Clots, cholesterol is not the damaging mechanism. Measuring the proportional relationship between HDL cholesterol and LDL cholesterol more accurately assesses the risk of atherosclerosis. The latest research shows that inflammation and free radicals cause damage to both the cholesterol and artery walls that initiates a natural repair sequence that results in the patching and build-up of calcium and cholesterol deposits. The marker that I believe will become the gold standard for risk is Homocysteine. This relates to cardiovascular risk in a much more precise way than cholesterol. A simple blood test indicates the risk and can be re-measured after a nutritional program to ascertain the effectiveness of the program.
This program shows that controlling free radicals is a more successful angle for preventing this major cardiovascular disease problem. This has more potential to provide much greater success than restrictive fat and cholesterol diets that have thus far failed.
How can Serracor-NK and Serra RX80 help?
Breaking it Down:
- Nattokinase - a well studied enzyme, famous for dissolving blood clots faster than any drug.
Nattokinase Research - Fibrinoyltic Activity
In vitro and in vivo studies have consistently demonstrated the potent fibrinolytic effect of Nattokinase.1 Research with nattokinase demonstrates that it may help avoid or reduce the likelihood of deep vein thrombosis, cardiac infarction, pulmonary emboli and stroke. It appears to accomplish this via its finbrinolytic, anti-inflammatory and modulating effect on blood pressure. Studies on hypertension demonstrate an average drop of 10.9% in Systolic Blood Pressure and a 9.7 percent drop in Diastolic Blood Pressure.2,3,4
A study conducted with natto on 12 healthy adults (6 men and 6 women, between the ages of 21 and 55) sought to demonstrate fibrinolytic activity. The volunteers were given 200 grams of natto (the food) before breakfast, then their fibrinolytic activity was tested over time. The results indicate natto generates an increased ability to dissolve blood clots. As a control, researchers later fed the same amount of boiled soybeans to the same volunteers and tracked their fibrinolytic activity. The tests showed no significant change.5
The accumulation of fibrin in blood vessels significantly increases the likelihood of thrombosis formation resulting in a cardiovascular event. For thrombolytic therapy, microbial fibrinolytic enzymes are now much more accepted. The physiochemical properties of this enzyme is becoming well characterized and its effectiveness in thrombolysis in vivo has been further identified.6,7
Nattokinase and Blood Clots
Blood clots (thrombi) form when strands of fibrin accumulate in the circulatory system. These clots can cause blockage of blood flow. If blood flow is blocked, the oxygen supply to that tissue is cut off and it eventually dies. In the heart, this can result in myocardial infarction (heart attack). In the brain, it can result in strokes or mini-strokes. Deep vein thrombosis can result in pulmonary emboli. All these events can be life-threatening. An in vitro study not only demonstrated the powerful fibrinolytic activity of nattokinase, but also showed the significant reduction in the aggregation of red blood cells and overall lowered whole blood viscosity. The net results are vascular conditions that are less likely to produce blood clots. The authors suggest that nattokinase possesses very real potential as a therapeutic agent in cardiovascular health.8
The process of forming a clot is complex and involves several enzymes. However, the body mainly produces one central enzyme for dissolving a clot, plasmin. It happens that the properties of nattokinase are very similar to plasmin. Nattokinase is particularly effective because it enhances the body's natural ability to fight blood clots in several different ways. It dissolves fibrin directly and appears to enhance the body's natural production of both plasmin and other clot-dissolving enzymes like urokinase. An in vivo study was undertaken to demonstrate the thrombolytic activity of nattokinase, plasmin and elastase on an induced clot in the common carotid artery of laboratory rats. The results indicate that the thrombolytic activity of nattokinase is stronger than that of plasmin or elastase in vivo in this model.9
A fascinating study was conducted to measure the effect of nattokinase in the prevention of deep vein thrombosis and superficial vein thrombosis on extended flights of 7-8 hours on high-risk individuals. The nattokinase group had no thromboses. The placebo group had 5 deep vein thromboses and 2 superficial vein thromboses or 7.6% of 94 individuals. After the flight, the degree of edema was increased by 12% in the placebo group and decreased by 15% in the nattokinase group. The authors concluded that nattokinase was effective in reducing thrombotic events and in controlling edema in high-risk subjects on long flights.10
Serrapeptase - (Peptizyme SP) is an enzyme derived from a species of bacteria originally found in the intestine of silkworms. The bacteria, Serratia mercesans produces the enzyme that enables the silkworm to dissolve its silken cocoon and emerge after metamorphosis. Serratia is now grown in cultures to produce serrapeptase by fermentation. Numerous research and clinical studies demonstrate serrapeptase's formidable anti-inflammatory, proteolytic (protein dissolving) and fibrinolytic (fibrin dissolving) properties. They also show that scar tissue is greatly reduced and proteins involved in the inflammatory process are effectively digested. Serrapeptase is a protease that has been used in Japan and Europe for over four decades for its anti-inflammatory activity.
BROMELAIN is a collective name for the proteolytic (protein-digesting) enzymes found in the pineapple plant (Ananas comosus), and is known for its digestive as well its anti-inflammatory properties. Because of its activity across a wide pH range, bromelain is a good substitute for pepsin and trypsin for both digestive and systemic support.*
PAPAIN is a widely used enzyme obtained from the latex of the fruit of the Papaya tree (Carica papaya). Papain has been used for centuries as an effective digestive aid.
LIPASE catalyzes the break-down of fats into essential fatty acids that are needed for healthy tissues and cells.*
PROTEASES are enzymes that hydrolyze (break-down) proteins like meat, casein, gelatin, soy, fish and other plant and animal proteins to smaller chains of polypeptides (small proteins) and amino acids for easier uptake throughout the body.
RUTIN is a bioflavonoid that strengthens and tones arteries and veins and provides antioxidant support against free-radicals and inflammation.*
AMLA, or Indian gooseberry (Emblica officinalis), is a natural and efficacious antioxidant. It is one of the richest sources of absorbable vitamin C available.
COENZYME Q10 is an essential enzyme and cofactor in metabolism that is naturally made and stored in the liver, kidneys, and heart. It is a vital part of energy production and overall cell health.*
MAGNESIUM is an essential mineral used as a cofactor by over 350 enzymes in the body. Magnesium is critical part of cardiovascular and nerve physiology. It helps relax arteries and assists in proper nerve impulse function.*